Biotin

Biotin is considered to occupy a chemical niche, metabolically speaking, with the B complex family of vitamins. It participates in various types of carboxylase reactions. In general, it has been shown to be helpful in improving structural integrity of bone connective tissue, nails, and hair.

It also seems to play a role in augmenting the regulation of blood sugar metabolism. In one study published in the Annals of New York Academy of Sciences, patients who were diabetic were taken off insulin and put on high doses of biotin (with a range of 10-20 mg) and found to do relatively well. High-dose biotin has been shown to be an effective aid in the augmentation and balancing of glucose metabolism. This was felt to be due to the fact that those who have diabetes or other types of blood sugar problems tend to have low biotin levels.

Biotin has been used as a nerve restorative agent, especially in the treatment of peripheral neuropathy. High doses of biotin, given orally, have been shown to be significantly helpful for peripheral neuropathy. In some clinical trials, use of injectable biotin as an intramuscular shot on a semi-daily basis, has been shown to be quite helpful.

Most over-the-counter nutritional supplements and multi-vitamins contain smaller amounts of biotin, in the 100-500-mcg range. Therapeutic doses, to help with blood sugar regulation and nerve function and healing, have often been in a much higher range of 5-10 mg. This is considerably higher than the usual over-the-counter microgram dosage. Higher doses are available at some health food stores and, locally, at Nora Apothecary and Dr. Azziz Pharmacy and by mail order through Optimal Wellness.

If you have further questions, please call the Advanced Medical Center.

Dale Guyer, M.D.